Methaqualone

Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant.

Methaqualone is a depressant that increases the activity of the GABA receptors in the brain and nervous system. When GABA activity is increased, blood pressure drops and the breathing and pulse rates slow, leading to a state of deep relaxation. These properties explain why Methaqualone was originally mainly prescribed for insomnia,[8] most commonly in 300 mg dosage.

Methaqualone peaks in the bloodstream within several hours, its effects generally lasting four to eight hours. Regular users build up a physical tolerance, requiring larger doses for the same effect. Overdose can lead to nervous system shut down, coma and death.